ISO 8655-1:2022

Overview

ISO 8655-1:2022 is the introductory part of the ISO 8655 series for piston-operated volumetric apparatus (POVA). It defines terminology, sets general requirements, and provides user recommendations for instruments such as pipettes, burettes, dilutors, dispensers and manually operated precision laboratory syringes. The standard clarifies concepts used across the series and establishes baseline expectations for calibration, testing and safe use. (It does not apply to medical products intended for use on humans, e.g., medical syringes.)

Key topics and technical requirements

ISO 8655-1:2022 focuses on foundational topics that support metrology and quality control for liquid handling:

• Terminology - standardized definitions (e.g., mean delivered volume, measurement uncertainty, dead volume, metrological confirmation) to ensure consistent interpretation across manufacturers and laboratories.
• General requirements - high-level rules covering:
  • frequency of calibrations and tests
  • reporting of measurement errors
  • handling of exchangeable parts
  • metrological confirmation (procedures to ensure POVA conform to intended use)
  • routine testing, maintenance and repair
  • criteria for suitability of performance statements and pass/fail determination
• Product information and marking - manufacturer’s user information, decontamination/sterilization guidance and chemical resistance data.
• Factors affecting device selection - interaction with different liquids, use of air-displacement pipettes, immersion depth and dead air/volume considerations.
• References to measurement procedures - the document points to gravimetric, photometric and alternative measurement procedures (ISO 8655-6, -7, -8) for determining delivered volume and estimating measurement uncertainty.

Practical applications and who uses it

ISO 8655-1 is essential for:

• Manufacturers developing and documenting POVA performance and issuing manufacturer declarations.
• Calibration laboratories and test houses performing independent calibration, verification and routine testing.
• Laboratory managers, QC personnel and end-users selecting, operating and maintaining pipettes, burettes and dispensers to meet process tolerances and traceability requirements.
• Regulatory and procurement teams specifying equipment acceptance criteria and conformity to metrological requirements.

Practical benefits include improved measurement traceability, consistent reporting of errors and uncertainties, and clearer guidance for maintenance and user safety.

Related standards

ISO 8655-1 is part of the ISO 8655 series; key normative references include:

• ISO 8655-2 to ISO 8655-5 (specific device requirements for pipettes, burettes, dilutors, dispensers)
• ISO 8655-6 (gravimetric reference procedure)
• ISO 8655-7, -8 (alternative/photometric procedures)
• ISO 8655-9 (manually operated precision laboratory syringes)

Keywords: ISO 8655-1, piston-operated volumetric apparatus, pipettes, calibration, measurement uncertainty, metrological confirmation, laboratory syringes.