ISO 12828-1:2011

Name: ISO 12828-1:2011 — Validation method for fire gas analysis — Part 1: Limits of detection and quantification
SKU: ISO 12828-1:2011
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Validation method for fire gas analysis — Part 1: Limits of detection and quantification

Название (английский):

ISO 12828-1:2011

Validation method for fire gas analysis — Part 1: Limits of detection and quantification

Статус документа:: Действующий
Формат:: Электронный (PDF)
Количество страниц:: 20
Дата публикации:: 23 ноября 2011 г.
Издание:: ISO IS 12828 edition 1 version 1
ICS:: 13.220.01

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Описание (английский):

In ISO 12828-1:2007, limits of detection and limits of quantification are defined and calculated. It provides methods for determining suitable values for these two parameters for a specific analytical procedure and for a specific chemical species. It does not provide detailed guidance on methods of sampling and analysis of specific species which might be present in fire effluents. This guidance is contained in ISO 19701 and ISO 19702.

Abstract

Похожие стандарты

Стандарты, упомянутые в описании

Overview

ISO 12828-1:2011 - Validation method for fire gas analysis, Part 1: Limits of detection and quantification - provides standardized guidance for defining and determining limits of detection (LOD) and limits of quantification (LOQ) for analytical methods used on fire effluents. It focuses on how to calculate suitable LOD and LOQ values for a specific analytical procedure and chemical species, helping laboratories and practitioners validate measurement methods without prescribing sampling techniques or species-specific analysis (see ISO 19701 / ISO 19702 for those details).

Key topics

Definitions and terms: Clear definitions for LOD and LOQ and associated notation, aligned with ISO vocabularies and measurement standards.

Risk concepts: Discussion of false positives (α risk) and false negatives (β risk) and why minimizing false negatives is critical in fire safety.

Practical criteria: Typical conventions-LOQ often taken as ~10 × standard deviation of blank; LOD often ~3 × standard deviation of blank (and LOQ ≈ 50% of repeatability in some contexts).

Validation methods: Three main approaches are described:

Main method 1 - determination from blank/matrix data
Main method 2 - determination from calibration linearity
Main method 3 - checking a prescribed quantification limit
Plus other secondary/alternative methods and examples

Validation workflow: Four-step process - define end-use, set required sensitivity/precision, select sampling and analytical method, then evaluate LOD/LOQ and uncertainty.

Reporting: Minimum requirements for presenting LOD/LOQ and how to express results near these limits to support reproducibility and inter-laboratory comparisons.

Applications and users

ISO 12828-1 is designed for:

Testing and calibration laboratories performing chemical analysis of fire effluents (helps meet ISO/IEC 17025 competence requirements).

Fire safety engineers using quantitative effluent data for toxicity indices or fractional effective dose (ISO 13571) and time-to-escape calculations.

Analytical chemists and QA managers who validate FTIR or other gas-analysis methods for smoke and toxicants.

Regulators and standard developers assessing method suitability, comparing methods in round-robin tests, or setting minimum LOQ for toxicity-based classifications.

Practical uses include method validation, setting quantification limits consistent with toxicological thresholds, ensuring comparability in inter-lab studies, and reliable reporting of low-level measurements in fire testing.

Related standards

ISO 19701 - Methods for sampling and analysis of fire effluents

ISO 19702 - Guidance for analysis of gases and vapours in fire effluents (FTIR)

ISO/IEC 17025 - Competence of testing and calibration laboratories

ISO 13571, ISO 13943, ISO 5725-1 - supporting guidance on toxicity, vocabulary and measurement accuracy

Keywords: ISO 12828-1:2011, LOD, LOQ, limits of detection, limits of quantification, fire gas analysis, validation method, fire effluents, ISO/IEC 17025, fire safety.

ISO 12828-1:2011

Abstract

Похожие стандарты

Overview

Key topics

Applications and users

Related standards

Технические детали

BS ISO 19701:2013

Methods for sampling and analysis of fire effluents.

ISO 19702:2015

Guidance for sampling and analysis of toxic gases and vapours in fire effluents using Fourier Transform Infra…

BS ISO 12828-1:2011

Validation method for fire gas analysis. Limits of detection and quantification.

BS EN ISO/IEC 17025:2017

General requirements for the competence of testing and calibration laboratories.

ISO 13571:2012

Life-threatening components of fire — Guidelines for the estimation of time to compromised tenability in fires

BS EN ISO 13943:2023

Fire safety. Vocabulary.

ISO 5725-1:2023

Accuracy (trueness and precision) of measurement methods and results — Part 1: General principles and definit…